The way I learned it, the event was the Pope having his hat knocked off, which happened within a few years of me hearing about The Game (and seemingly a few more times since).
Since then I have simply stayed winning according to my arbitrary ruleset.
For anyone wondering if this was someone’s real opinion as a comic, it’s satire.
This is by Ward Sutton for the Onion, under the pseudonym Stan Kelly. He does a lot of these satire-of-conservatives cartoons.