(biologist - artist - queer)

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You’re the only magician that could make a falling horse turn into thirteen gerbils

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Joined 1 year ago
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Cake day: June 10th, 2023

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  • You didn’t mention it, but have you considered how it would feel if you had a bad day and didn’t live up to this standard?

    You’re framing it like a moral philosophy, but feeling anger is not a morally bad thing. Neither is jealousy, or selfishness, at times. It’s just part of the human experience, and we can avoid it most of the time, but occasionally we’re going to need to focus on ourselves and our needs and our feelings.

    Similarly, it’s impossible to avoid having an ego 100% of the time. Honestly, it sounds like this quality is part of your identity-- would you like yourself less if you lived up to this standard imperfectly?

    I don’t think it’s unusual to want to be a good person and to want to control our worst impulses. But to describe it as “trying to act like a saint”, and saying you’re “deaf to your own needs”-- those are concerning statements.

    I don’t think anyone can speak for you or guess what’s going on from the outside. But if I were you, I’d be exploring if there’s fear underlying these impulses. Fear of judgment: how do you think the world would perceive you if you stopped being so strict about it? Fear of badness: how does it feel when you have a bad day and you fail to be perfect? Do you resent yourself? Fear of impurity: do you feel like other people are bad when they have these natural reactions? Do you fear being like other people who are experiencing and dealing with normal feelings?




  • Oooooh I have some ideas! Some of these are paid/premium (but NOT micro transactions) and some have mild ads. But I share the distaste for data-mining, money grubbing, brain-melting-ad-ridden games, so I’m certain they are on the least intrusive end of the spectrum.

    I really love biology (I’m a biologist…) so these are both pet games and usually breeding/evolution games!

    • Fish Tycoon – This one specifically. A classic! Breed and care for cute fish!
    • Niche breed and evolve – so neat and pretty educational about evolution/genetics. There’s a slightly more complicated/difficult pc game if she decides she likes the nichelings/universe.
    • Pocket Frogs – Simple, low stress collecting game. it would take years to collect all the frogs, and there’s a relatively active community of people who trade sets of frogs to other people to help them complete collections. Would be fun to play with her friends at school!
    • Reigns Her Majesty – a game about running a kingdom as a queen. When you die, you become your heir and retain some progress from your last lives. It doesn’t fit the exact criteria you mentioned, but I think she might like it anyway!

  • because the very first thing you say in this post basically amounts to “I think I have the authority to decide the basis on which we determine who deserves to vote”

    like, yeah, most people can navigate to their secretary of state websites. And it’s not really your responsibility to have to link the pages anyway.

    But doing it for that reason aligns you philosophically with people who think that the illiterate, the elderly, the poor, the disabled, the critically ill, etc. somehow don’t deserve to vote. It aligns you ideologically with other people who think they can decide who deserves to vote, with people who want to disenfranchise others-- in essence, it aligns you ideologically with many Republicans




  • stoneparchment@possumpat.iotoMemes@lemmy.mlThis is the way
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    7 months ago

    I feel like I’ve seen this take a lot more in the past ~5 years than I did before. Not just that zoos are unethical, but that any animal ownership (or really interaction of any kind) is inherently abusive.

    You’re certainly entitled to feel however you want about animal ownership and act accordingly, but personally I feel like it’s honestly kind of a weird take?

    Humans are obviously not the only species that develops symbiolotic relationships with other organisms (in a diversity of power dynamics), but we are also not the only species who take on specifcally ownership or shepherd roles for other species (like spiders with frog pets, or fungus farmer ants, among many many other examples). Thus, the ontological position this opinion must operate from is that humans are somehow distinct and superior to nature, such that we have separate and unique responsibilities not to engage in mutualistic ownership with other organisms, on the basis that like, we’re somehow “above” that? That we’re so enlightened and knowledgeable that we exist in a category of responsibility distinct from all other organisms?

    Of course, a lot of our relationships to animals can be described as harmful in other terms without needing to take this specific stance. Like, our relationship with many agricultural animals can be critiqued through the harm done to their individual well-beings and through the harm their propagation does to the global environment. Or irresponsible pet owners can be critiqued for how their unwillingness to control the reproduction or predatory abilities of their pets can harm local ecosystems, like an introduced invasive species might. Or valid criticisms of many zoos when they prioritize profits over animal welfare, rehabilitation, ecosystem restoration, and education. Or that the general public picking up wild animals is a problem because it disturbs their fragile ecosystems and traumatizes them, especially when done on the large scale of human populations (but distinctly not for ecological study, wild animal healthcare, education, etc., like Steve Irwin et. al) But none of these are specific criques of the mutualistic ownership relationship itself as much as problems with the way we handle that relationship.

    Idk, I’m interested to understand your opinion, especially if it has detail I’m missing beyond “we shouldn’t have pets, zoos, or farms because we’re better than that”!





  • That’s valid! I agree. I think in this case it would be reasonable for the model to give multiple (or like, at least one, jeez) images with white queens. I don’t disagree with anyone in that sense. I just also don’t think it’s worth pitching a fit when the dumbass model that has been trained to show more racial diversity produces (frankly comical) hallucinations.

    The ethos of the trainers is a good one. Attempting to counter the (demonstrated, measurable) bias of many models toward whiteness is a good choice. I prefer that the trainers choose to address the bias even if it (sometimes, in early versions) makes the model make silly mistakes like this. That’s all.


  • stoneparchment@possumpat.iotoLemmy Shitpost@lemmy.worldAI or DEI?
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    9 months ago
    • it’s true that this would mislead children, but the model could hallucinate about literally anything. Especially at this stage, no one-- children or adults-- should be uncritically accepting what the model states as fact. That said, I agree LLMs need to improve their factual accuracy

    • Although it is highly debated, some scholars suggest Queen Charlotte might have had African ancestry, or that she would be considered a POC by today’s standards. Of course, she reigned in the 17-1800s, but it isn’t entirely outlandish to have a “Queen of Color”, if we aren’t requesting a specific queen or a specific race

    • People of color did live in England in the middle ages? Like not diverse in the way we conceive now, but here are a few papers discussing the racial diversity at the time. It was surely less intermingled than today, but it’s not like these images are impossible

    • Other things are anachronistic or fantastical about these images, such as clothing. Are we worried about children getting the wrong impression of history in that sense?

    • Of course increasing visibility and representation of all kinds of marginalized people is important. I, myself, am disabled, so I care about that representation too-- thanks for pointing out how we could improve the model further. I do kinda feel like people would be groaning if the model had produced a Queen with a visible disability, though… I would be delighted to be wrong on this front :)


  • stoneparchment@possumpat.iotoLemmy Shitpost@lemmy.worldAI or DEI?
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    9 months ago

    It’s also like, I guess I would prefer it to make mistakes like this if it means it is less biased towards whiteness in other, less specific areas?

    Like, we know these models are dumb as rocks. We know that they are imperfect and that they mirror the biases of their trainers and training data, and that in American society that means bias towards whiteness. If the trainers are doing what they can to prevent that from happening, whatever, that’s cool… even if the result is some dumb stuff like this sometimes.

    I also don’t think it’s a problem for the user to specify race if it matters? Like “a white queen of England” is a fine thing to ask for, and if it isn’t specified, the model will include diverse options even if they aren’t historically accurate. No one gets bent out of shape if the outfits aren’t quite historically accurate, for example



  • When I say “the cell isn’t a machine”, it is in specific reference to the machine model of the cell, which is a previously established conceptual framework in the field of molecular biology. If you want to understand why that model is falling out of favor today, you’re invited to read the article linked by OP and/or the articles I have linked in other comments.

    The gist is that the cell is more complicated, flexible, and emergent than any machine has ever been and will be for the foreseeable future, and the idea that we can simply map the functions of each molecule in the cell to get a perfect “circuit diagram” of how everything plays together is defunct.

    I don’t have time to mess with this thread any more. You can either accept what myself (an expert in this field), the author of this publication (which happens to be one of the most prestigious journals in the world), and others who do this research daily are saying about this, or you can not. Frankly, if you are an expert also, the field, the research, and the truth barely cares about our opinion-- it certainly doesn’t care about non-expert opinions on the internet.


  • Junk DNA is repeating codons, or codons that occur in areas that are outside of the “start/stop” codon triplicate pairs.

    Those sequences do things and have effects. In fact, the coding regions are often less functional than the non-coding ones.

    They aren’t there for structural reasons, all DNA is the same 4 codons linked together over and over, all the different chromosomes are different sizes.

    Sometimes they ARE there for structural reasons? Read: enhancers, or CTCF binding sites? Among many other myriad examples of functional noncoding regions? Also, nucleotides =/= codons. There are 64 codons.

    All of this DNA is reported when the cells divide, that’s the only time those regions between the stops and starts actually come into play. This is very easily proven, we know the structure of the reading proteins down to the molecule (indeed there are starts and stops and triplicate base pairs that design these transcribing proteins).

    That’s bull. You’re out of your depth. A contemporary college molecular biology course would show your examples to the contrary.

    The “important” junk DNA that has significance while not being in a “start->stop” zone are the codons that occur before the first start codon on either side of a DNA strand, when DNA is replicated the protein that starts replicating it has to start at 1 end of 1 side of the DNA in order to be able to read it

    I feel like a broken record but Enhancers! lncRNAs! siRNAs! Binding sites! Other gene regulatory regions! Epigenetic nucleosome modifications! Chromatin remodeler sites!

    except it needs to find the end first, and to make sure it’s all the end it “clips” the first 6 (? Maybe more maybe less, it’s been decades since I’ve studied this)

    Oh, there’s your problem. A lot has changed. You refuse to see the sea change happening around you because it means you’re out of date.

    Sorry for the wall of text, but there’s plenty of examples of blatantly junk DNA, and there are known methods of how it occurs. Anyone who says every codon pair has a purpose has a screw loose and is ignorant to the mechanics of evolution.

    I was happy to reply to you and engage pleasantly originally but you are only engaging with people that know less about biology than you do. You are not an expert if you last studied biology decades ago and can’t remember the details. You certainly aren’t enough of an authority on the subject to question a contemporary article published in Science or the work of other researchers currently in the field.

    I really, really encourage you to read these papers thoroughly. You are the target audience-- people who learned the machine model of the cell and who are gripping it so tightly that they are blind to the nuance that we’ve uncovered. I also encourage you to not write insults about people who disagree with you, especially people with more domain knowledge than you have.


  • This is a funny comment though, because “junk” DNA is involved with epigenetic regulation and cellular behavior.

    “It’s there so it must have function”, “it’s still in the genetic code so it must have been selected for” is the least nuanced take,

    “It’s there just randomly and therefore is junk”, and “evolution does not select for efficiency” is an improvement,

    But “it’s there and it’s doing something despite not having a bespoke, prescribed function” and “evolution is a cascade of emergent effects and random chance, none of our genome is non-functional even though it is random” is the most up to date take

    You seem like a biologist, why not go read some of these papers? Like the one I linked by Dan Nichols? Most people don’t have the background necessary to understand the language (no shade) but you seem to!


  • I would encourage you to read the linked Science paper and Dan Nichol’s paper, Is the Cell Really a Machine?

    You feel that if a codon isn’t meant for something, if it doesn’t have a purpose– then it is junk. This is a mindset that is reflective of the machine model of the cell. We used to expect that each protein was bespoke for a function, each transcript necessary.

    The whole paradigm shift at hand is this model falls flat, even for coding regions. I think you’re actually very spot in here with the prokaryotic DNA or the plant genomes (love me some violets for their weird genomes). Some parts of a genome will rapidly change and appear to serve no real purpose, but the next bite is the important one: even if it seems like there isn’t a purpose, like a top-down prescription for functionality, those regions are still doing something while they are present.

    For example, some long non-coding regions affect the likelihood that a person will develop Parkinson’s disease, or in the case of plants with various polyploidies, the relative expression of their genes won’t necessarily change, but the absolute expression may.

    Basically, you aren’t wrong that these regions dont have a purpose, because no genes have a purpose. The cell isn’t a machine.