Yeah, they’re partly genetic but you can risk it. I have a couple of friends who have had their third or fourth stone and I’ve never felt so much as a slight discomfort on my kidneys. It makes me wonder wtf they’re doing to themselves but I’m not one to judge.

That was definitely the cause of my kidney stone, because I don’t take OTC pain meds frequently, but if you do have ways to avoid kidney stones, avoid kidney stones. They are no fun.

Was he on narcotics? I’m finding no link between Acetaminophen or Ibuprofen to kidney stones. Just drink more water.

https://www.utsouthwestern.edu/newsroom/articles/year-2023/june-prevent-kidney-stones.html

https://pubmed.ncbi.nlm.nih.gov/30829133/

Ibuprofen is mostly processed by your liver as well. Acetaminophen uses a bit of both.

This appears to occur predominantly systemically in the liver [1,10], but may occur pre-systemically in the gut as well [11]. Ibuprofen is almost completely metabolized, with little to no unchanged drug found in the urine [1,9,12].

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355401/

Acetaminophen (APAP) is normally metabolized in the liver and kidney by P450 enzymes. No toxicity is observed with therapeutic doses of APAP.

https://www.goodrx.com/acetaminophen/is-tylenol-acetaminophen-bad-for-your-liver-or-kidneys

https://pubmed.ncbi.nlm.nih.gov/8669426/

Tylenol (acetaminophen) is almost completely broken down by the liver. During this process, a toxic chemical forms. Normally, the liver makes it non-toxic. But if you take too much Tylenol, the liver can’t properly process it all. The toxic chemical can then build up and poison liver cells.

https://www.goodrx.com/acetaminophen/is-tylenol-acetaminophen-bad-for-your-liver-or-kidneys